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#Prota lyn review how to

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Over 8,300 of our antibodies are offered as ImmunoCruz ® conjugates which eliminates the need for a secondary antibody. Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Hematopoietic tissues predominantly express Lyn, which influences normal immunoglobulin production and regulation. The human Lyn gene maps to chromosome 8q12 and encodes a 505 amino acid protein. Src-family kinases are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Src-family kinases contain an amino terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility, and adhesion.

By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src is the first proto-oncogenic non-receptor tyrosine kinase characterized in human. Src is the human homolog of the v-src gene of the Rous sarcoma virus, also known as avian sarcoma virus or ASV.

Lyn Antibody (H-6) is available as both the non-conjugated anti-Lyn antibody form, as well as multiple conjugated forms of anti-Lyn antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor ® conjugates. Lyn Antibody (H-6) is a high quality monoclonal Lyn kinase antibody (also designated Lyn tyrosine kinase antibody, LYN proto-oncogene, Src family tyrosine kinase antibody, p53Lyn antibody, or p56Lyn antibody) suitable for the detection of the Lyn protein of mouse, rat and human origin. These reagents are now offered in bundles with Lyn Antibody (H-6) ( see ordering information below).

m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Lyn Antibody (H-6) for WB and IHC(P) applications.

#Prota lyn review how to

Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Lyn (H-6): sc-7274.

also available conjugated to Alexa Fluor ® 680 or Alexa Fluor ® 790 for WB (NIR), IF and FCM for use with Near-Infrared (NIR) detection systems, such as LI-COR ®Odyssey ®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems.

also available conjugated to Alexa Fluor ® 488, Alexa Fluor ® 546, Alexa Fluor ® 594 or Alexa Fluor ® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems.

Anti-Lyn Antibody (H-6) is available conjugated to agarose for IP HRP for WB, IHC(P) and ELISA and to either phycoerythrin or FITC for IF, IHC(P) and FCM.

Anti-Lyn Antibody (H-6) is recommended for detection of Lyn p56/p53 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA.

specific for an epitope mapping between amino acids 44-63 near the N-terminus of Lyn of human origin.

Anti-Lyn Antibody (H-6) is a mouse monoclonal IgG 2a κ Lyn antibody, cited in 111 publications, provided at 200 µg/ml.

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BIOLOGICALLY ACTIVE & PURIFIED PROTEINS.PROTEIN A, G-PLUS & L AGAROSE IP REAGENTS.ISOTYPE SPECIFIC MOUSE IgG BINDING PROTEINS.POLYCLONAL GOAT/RABBIT ANTI-MOUSE SECONDARY ANTIBODIES.MONOCLONAL MOUSE ANTI-RABBIT/GOAT SECONDARY ANTIBODIES.